Scientists use cell death, whether by apoptosis or necrosis, to evaluate the toxicity or effectiveness of substances of interest, including potential therapeutic agents. For example, researchers will ...

Safety, tolerability, and preliminary pharmacokinetic/pharmacodynamic profile of JMT103 in patients with bone metastases from solid tumors: A multicenter, open-label ...

Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex that ...

Cells in our body are programmed to die after a certain period of time—a natural process known as apoptosis or “cell suicide.” This process is essential for maintaining the body’s balance. When aged ...

Apoptosis is a carefully regulated process that can be influenced by many factors, and thus tracking and monitoring these processes is a vital and regular part of biological research. Flow cytometry ...

Proper, efficient regulation of cellular development is essential for a living organism. Cells have to constantly be removed and recycled, with new cells replacing them all the time. One such process ...