Many diseases are driven by proteins interacting with each other inside cells. But blocking these interactions with drugs is ...
Cyclic peptides, the WuXi analysis says, are a transformative class of therapeutics that combine the advantages of small ...
A new method screens large libraries of synthetic cyclic peptides to identify compounds that can enter cells for therapeutic effect.
Membrane-permeable cyclic peptide that inhibits the intracellular Keap1-Nrf2 protein-protein interaction. Credit: Christian ...
CycPeptMPDB, a novel database—created by Tokyo Tech researchers—focused on the membrane permeability of cyclic peptides, could accelerate the development of drugs based on these promising compounds.
Scientists at the Ecole Polytechnique Fédérale de Lausanne (EPFL) have addressed a long-standing challenge in the pharmaceutical industry, with the development of a two-step, one-pot method for ...
For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat ...
For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat ...
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