Wednesday's flight marks humanity's first trip to the moon since the Apollo program ended in 1972. If successful, it will pave the way for Artemis IV, NASA’s first crewed moon landing since Apollo 17 in December 1972, and eventually a sustained presence on the moon and human exploration to Mars and beyond.

NASA's Artemis II mission is set to launch, sending four astronauts on a 10-day journey around the moon. Here's how to watch it live.

Laurie Leshin, professor with ASU’s School of Earth and Space Exploration, spoke about how the Artemis II launch brings NASA one step closer to sending people to the moon again.

The Space Launch System rocket, which is being used by Artemis II, is unusual in that Congress, frustrated when President Obama canceled an earlier return-to-the-moon program called Constellation, gave detailed specifications for what it wanted NASA to build. The pieces of S.L.S. are, in large part, a remix of components of the space shuttles.

A NASA official explains the goals, training and significance behind the first crewed lunar mission in more than 50 years.

Meet the crew, learn about the mission, and understand why this is an incredibly important giant step forward.

Boeing's biggest role in Project Artemis could soon be obsolete.

Faced with the imminent retirement of the International Space Station, NASA is pushing to speed up work on its potential replacements