Tumor cells can lapse into a sleep-like state and thereby evade the destructive effect of cancer drugs. In some types of the ...

Summary: A developmental neurobiology breakthrough uncovered a previously unmapped molecular pathway that regulates brain ...

Glucocorticoid receptor pathway targeting with relacorilant represents a novel therapeutic mechanism in oncology, showing clinical benefit in platinum-resistant ovarian cancer when paired with ...

Researchers have discovered a new way that brain plasticity is controlled in early life, offering insight into the ...

Researchers from ETH Zurich have developed a molecular switch that is controlled by light. It wakes lung cancer cells up from a protective dormant state so that they are more accessible for treatment.

Glucocorticoids are steroid hormones synthesised by the adrenal cortex that exert potent anti-inflammatory and immunomodulatory effects through the glucocorticoid receptor (GR). In the absence of ...

New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance ...

Harvard Medical School researchers identified a cortisol-driven pathway that regulates critical-period closure in the developing brain. In mice, stress hormones activated astrocytes and promoted ...

Congenital adrenal hyperplasia treatment took a significant step forward at ENDO 2026, where Crinetics’ atumelnant — an oral ...

More than 44% of individuals receiving high doses of prolonged glucocorticoid medication develop osteonecrosis, with the femoral head being the most commonly affected site, predominantly in those aged ...