Causal inference in observational settings seeks to estimate the effect of exposures, treatments or interventions on outcomes in the absence of random assignment. Unlike experimental designs, ...

CHICAGO -- A study comparing different statistical methods used to remove the effects of selection bias in observational studies finds that results may vary and caution may be warranted when ...

Observational studies are critical in evaluating the long-term safety and effectiveness of new therapies on patients’ lives. However, two major shifts are significantly changing the research ...

Protocol amendment for ENSEMBLE study: A multicenter, randomized, phase III trial to test the superiority of consolidation irinotecan, capecitabine and oxaliplatin vs capecitabine and oxaliplatin ...

In the article that accompanies this editorial, Lu et al 5 conducted a systematic review on the use of instrumental variable (IV) methods in oncology comparative effectiveness research. The main ...

Medical research is essential for advancing the understanding of health, diseases, and treatments. There are many types of studies that serve different purposes. Medical research, or health research, ...