In Alzheimer’s disease, brain damage is often linked to a mix of problems, including beta-amyloid buildup, tau pathology, ...

TTUHSC’s Petar Grozdanov, Ph.D., will investigate how perturbed gene expression in the brain can contribute to neurodegenerative disorders such as Alzheimer’s disease. More than six million Americans ...

The field of protein dynamics and allosteric regulation explores how proteins, far from being rigid entities, exhibit a wide range of motions that are integral to their function. These molecular ...

Lysine acetylation is a reversible post-translational modification that plays a critical role in modulating protein function, stability and interactions across a range of organisms. This modification, ...

Exploring the genetic blueprint of cerebrospinal fluid proteins, this study uncovers new markers and therapeutic targets that may unlock advancements in Alzheimer’s diagnosis and care. Study: ...

Leucine-rich repeat kinase 2 (LRRK2) has emerged as a critical player in both neurological and peripheral diseases. In a ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

Cancer cells are metabolic opportunists, bending every pathway to fuel unchecked growth. Now UCLA scientists show that a single protein—Insulin-like Growth Factor 2 mRNA-Binding Protein 3 ...

Incidence and survival trends in early-onset colorectal cancer. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a full text component.

In the intricate regulation of inflammation, metabolic reprogramming and posttranslational modification (PTM) have emerged as pivotal players, offering new avenues for understanding the fine-tuned ...