Breaks and rearrangements in the genome can lead to severe diseases, even if all genes remain intact. Hi-C, a method to map the three-dimensional structure of chromosomes, promises more reliable and ...

Tokyo, Japan – Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion. They trained a convolutional neural ...

System schematic for automatic detection of sister chromatid exchanges. Machine learning techniques have been used to develop a set of algorithms that can identify and count SCEs in microscopy images.

(A) Stained, diploid spread of chicken metaphase chromosomes. (B) Same spread after multicolor FISH with pseudocolored chromosomes. (C) Probes were detected using antibodies. (D) Mid-plane light ...