Chromosomal translocations of the human MLL (mixed lineage leukemia) gene create two reciprocal fusion genes, which encode chimeric MLL fusion proteins. Currently, more than 40 different translocation ...

The MLL-AF4 fusion protein, which causes the blood cancer called mixed-lineage leukemia, binds to several genes responsible for early blood cell development. MLL-AF4 also alters the chromatin proteins ...

The lack of obvious functional similarity between the MLL fusion partners led us to study the subcellular localization of the most common MLL fusion partner AF4. In addition, we have sought to isolate ...

Light scattering instrumentation is widely used in the characterization of macroparticles and nanoparticles in solution. It provides cutting edge tools for determining absolute molar mass, size, ...

Postnova Analytics reports on exciting advances in the analysis of plasma proteins using a hyphenated system that couples asymmetric flow Field-Flow Fractionation (AF4) and inductively coupled ...