A cellular-resolution map of prenatal brain development in Down syndrome reveals disrupted neuron production timing and altered cell types.

Scientists mapped human brain development in Down syndrome at a cellular level, discovering that stem cells "rush" to become ...

Scientists at UCLA have created one of the first cellular-resolution molecular maps detailing how Down syndrome alters human brain development before birth—a resource that resolves longstanding ...

Key takeawaysUCLA researchers created a single-cell map of the developing human neocortex in Down syndrome during a critical ...

A recent study suggests that Neanderthal brains developed differently from modern human brains in a subtle but important way.

UCLA scientists have produced one of the first high-resolution molecular maps showing how Down syndrome disrupts human brain development before birth. The study analyzed over 100,000 nuclei from ...

Neurons that fire together, wire together” is not the full story. A novel mechanism explains how the brain can learn across ...

Clinically meaningful efficacy demonstrated in the 8-week follow-up period (weeks 9-16), with a 90% median reduction in clinical seizures over ...

This is a useful study that seeks to elucidate the molecular mechanisms underlying spinal motor circuit assembly. The authors demonstrate that loss of Onecut transcription factors in spinal motor ...

This valuable study addressed a key question in epilepsy research: whether the recordings of very fast oscillations in the brain (>250Hz, fast ripples) reflect underlying pathology or might be a ...