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Grignard Reagent Reaction Mechanism
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The Grignard reaction enables the formation of C-C bonds via nucleophilic addition of organomagnesium species to electrophilic carbon centers. Discovered by Victor Grignard in the early 20th century, the reaction proceeds through single-electron transfer during oxidative insertion of magnesium into the C-X bond, generating an organomagnesium intermediate that adds to carbonyl compounds, followed by acidic workup to yield alcohols. Learn · Review · Repeat
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